Yanfei Wang

Yanfei Wang

Assistant Scientist working on causal inference, target trial emulation, and longitudinal clinical modeling with real-world healthcare data.

Publications

This page highlights selected publications that reflect my current research direction in causal inference, target trial emulation, and longitudinal clinical modeling. For a full and updated list, please see my Google Scholar profile.

An operational target trial simulation framework for clinical information using electronic health records

Yanfei Wang, Yi Guo, Yongqiu Li, Tuo Lin. 2026. npj Digital Medicine.
An operational framework for reconstructing clinically meaningful target trial objects from routine EHR data, with emphasis on action reconstruction, decision-time alignment, and empirical support.
DOI | Code

Integration of Genetic and Imaging Data for Alzheimer’s Disease Diagnosis and Interpretation

Wang Y., Wang Q., Zhou M., et al. 2025. Advanced Science, 12(41), e07629.
A multimodal framework integrating genetic and imaging information for Alzheimer’s disease diagnosis and interpretation.

Wang Y., Guo Y., Tan A. C., et al. 2025. npj Precision Oncology, 9(1), 346.
A real-world analysis of immune-related adverse events in patients treated with immune checkpoint inhibitors.

Revealing Chronic Disease Progression Patterns Using Gaussian Process for Stage Inference

Wang Y., Zhou X., et al. 2023. Journal of the American Medical Informatics Association.
A longitudinal modeling study using Gaussian process methods to characterize chronic disease progression patterns.

Additional selected work

  • Wang Y., Zhou X., et al. (2022). Phenotype-Genotype analysis of Caucasian patients with high risk of osteoarthritis. Frontiers in Genetics, 13, 922658.
  • Wang Y., Zhou X., et al. (2020). Causal Discovery in Radiographic Markers of Knee Osteoarthritis and Prediction for Knee Osteoarthritis Severity with Attention-Long-Short-Term Memory. Frontiers in Public Health, 8, 604654.
  • Feng Y., Yi J., Wen J., Wang Y., et al. (2023). COV2Var, a function annotation database of SARS-CoV-2 genetic variation. Nucleic Acids Research.
  • Wu S., Zhang J., Wang Y., et al. (2024). metsDB: a knowledgebase of cancer metastasis at bulk, single-cell and spatial levels. Nucleic Acids Research.
  • Liu X., Wang Q., Zhou M., Wang Y., et al. (2024). DrugFormer: Graph-Enhanced Language Model to Predict Drug Sensitivity. Advanced Science, 11(40), 2405861.
  • Luo R., Chyr J., Wen J., Wang Y., et al. (2023). A novel integrated approach to predicting cancer immunotherapy efficacy. Oncogene, 42, 1913 to 1925.
  • Deng Y., You L., Wang Y., Zhou X. (2021). A Coarse-to-Fine Framework for Automated Knee Bone and Cartilage Segmentation Data from the Osteoarthritis Initiative. Journal of Digital Imaging, 34(4), 833 to 840.
  • You L., Deng Y., Wang Y., et al. (2022). A novel sagittal craniosynostosis classification system based on multi-view learning algorithm. Neural Computing and Applications, 34, 14427 to 14434.
  • Wang Q., Feng Y., Wang Y., et al. (2024). AntiFormer: graph enhanced large language model for binding affinity prediction. Briefings in Bioinformatics, 25(5), bbae403.

Ongoing methodological work